Charles Shyng Selected Research

2- (4- (4- methyl- 6- phenylpyridazin- 3- yl)piperazin- 1- yl)pyrimidine

9/2014

An anti-neuroinflammatory that targets dysregulated glia enhances the efficacy of CNS-directed gene therapy in murine infantile neuronal ceroid lipofuscinosis.

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Charles Shyng Research Topics

Disease

3	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 01/2017 - 09/2014
2	Disease Progression 01/2018 - 01/2017
2	Lysosomal Storage Diseases (Lysosomal Storage Disease) 10/2014 - 09/2014
2	Gliosis 10/2014 - 09/2014
1	Angelman Syndrome (Syndrome, Angelman) 10/2021
1	Neurodevelopmental Disorders 01/2018
1	Atrophy 09/2014
1	Alzheimer Disease (Alzheimer's Disease) 09/2014
1	Neuroinflammatory Diseases 09/2014
1	Traumatic Brain Injuries (Traumatic Brain Injury) 09/2014

Drug/Important Bio-Agent (IBA)

3	Proteins (Proteins, Gene)FDA Link 01/2017 - 09/2014
2	EnzymesIBA 01/2017 - 10/2014
1	Protein Isoforms (Isoforms)IBA 10/2021
1	palmitoyl-protein thioesteraseIBA 01/2017
1	HydrolasesIBA 01/2017
1	VimentinIBA 10/2014
1	Kainic Acid (Kainate)IBA 09/2014
1	CytokinesIBA 09/2014
1	Lysergic Acid Diethylamide (LSD)IBA 09/2014
1	2- (4- (4- methyl- 6- phenylpyridazin- 3- yl)piperazin- 1- yl)pyrimidineIBA 09/2014

Therapy/Procedure

2	Therapeutics 01/2018 - 01/2017